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1

Immunomodulatory activity and non-specific suppressor cell generation by spirogermanium in murine and rat models of cell-mediated immunity

Alison M. Badger, Michael J. DiMartino, Swift Barbara A., Mirabelli Christopher K.

Journal:

Immunopharmacology

Year:

1988

Language:

english

File:

PDF, 744 KB

english, 1988

2

IL-1- and TNF-induced bone resorption is mediated by p38 mitogen activated protein kinase

Sanjay Kumar, Bartholomew J. Votta, David J. Rieman, Alison M. Badger, Maxine Gowen, John C. Lee

Journal:

Journal of Cellular Physiology

Year:

2001

Language:

english

File:

PDF, 241 KB

english, 2001

3

Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis

Alison M. Badger, Don E. Griswold, Rasesh Kapadia, Simon Blake, Barbara A. Swift, Sandy J. Hoffman, George B. Stroup, Edward Webb, David J. Rieman, Maxine Gowen, Jeffrey C. Boehm, Jerry L. Adams, John

Journal:

Arthritis & Rheumatism

Year:

2000

Language:

english

File:

PDF, 1.14 MB

english, 2000

4

Disease-modifying activity of SB 273005, an orally active, nonpeptide αvβ3 (vitronectin receptor) antagonist, in rat adjuvant-induced arthritis

Alison M. Badger, Simon Blake, Rasesh Kapadia, Susanta Sarkar, Joshua Levin, Barbara A. Swift, Sandy J. Hoffman, George B. Stroup, William H. Miller, Maxine Gowen, Michael W. Lark

Journal:

Arthritis & Rheumatism

Year:

2001

Language:

english

File:

PDF, 1.11 MB

english, 2001

5

Disease-modifying activity of SK&F 106615 in rat adjuvant-induced arthritis. Multiparameter analysis of disease including magnetic resonance imaging and bone mineral density measurements

Jeremy N. Bradbeer, Rasesh D. Kapadia, Susanta K. Sarkar, Hugh Zhao, George B. Stroup, Barbara A. Swift, David J. Rieman, Alison M. Badger

Journal:

Arthritis & Rheumatism

Year:

1996

Language:

english

File:

PDF, 1001 KB

english, 1996

6

Down-regulation of chondrocyte aggrecan and type-II Collagen gene expression correlates with increases in static compression magnitude and duration

Paula M. Ragan, Alison M. Badger, Michael Cook, Vicki I. Chin, Maxine Gowen, Alan J. Grodzinsky, Michael W. Lark

Journal:

Journal of Orthopaedic Research

Year:

1999

Language:

english

File:

PDF, 806 KB

english, 1999

7

Inhibition of caspase-3-like activity prevents apoptosis while retaining functionality of human chondrocytes in vitro

Mark E. Nuttall, Daniel P. Nadeau, Paul W. Fisher, Feilan Wang, Paul M. Keller, Walter E. Dewolf Jr., Mary B. Goldring, Alison M. Badger, Dennis Lee, Mark A. Levy, Maxine Gowen, Michael W. Lark

Journal:

Journal of Orthopaedic Research

Year:

2000

Language:

english

File:

PDF, 864 KB

english, 2000

8

Augmentation of concanavalin A-induced immunosuppression by indomethacin

Alison M. Badger, Don E. Griswold, Donald T. Walz

Journal:

Immunopharmacology

Year:

1982

Language:

english

File:

PDF, 793 KB

english, 1982

9

Generation of suppressor cells in normal rats by treatment with spirogermanium, a novel heterocyclic anticancer drug

Alison M. Badger, Christopher K. Mirabelli, Michael DiMartino

Journal:

Immunopharmacology

Year:

1985

Language:

english

File:

PDF, 495 KB

english, 1985

10

Induction of suppressor cell activity in vivo and suppression of lymphoproliferative responses in vitro by SK&F 105685 in the dog

Patricia A. Thiem, Johanne M. Kaplan, Peter J. Bugelski, Elizabeth V. Ruggieri, Alison M. Badger

Journal:

Immunopharmacology

Year:

1992

Language:

english

File:

PDF, 715 KB

english, 1992

11

Reversal of histamine-mediated immunosuppression by structurally diverse histamine type II (H2) receptor antagonists

Alison M. Badger, Jean Young, George Poste

Journal:

International Journal of Immunopharmacology

Year:

1984

Language:

english

File:

PDF, 457 KB

english, 1984

12

Suppressor cell induction by the anticancer drug spirogermanium

Alison M. Badger, Michael J. DiMartino, Thomas C. Schmitt, Barbara A. Swift, Christopher K. Mirabelli

Journal:

International Journal of Immunopharmacology

Year:

1987

Language:

english

File:

PDF, 705 KB

english, 1987

13

Inhibition of animal models of autoimmune disease and the induction of non-specific suppressor cells by SK&F 105685 and related azaspiranes

Alison M. Badger, Michael J. DiMartino, James E. Talmadge, Donald H. Picker, David A. Schwartz, James W. Dorman, Christopher K. Mirabelli, Nabil Hanna

Journal:

International Journal of Immunopharmacology

Year:

1989

Language:

english

File:

PDF, 614 KB

english, 1989

14

Induction of non-specific suppressor cells and myeloregulatory effects of an immunomodulatory azaspirane, SK&F 105685

Andrew G. King, Diane Olivera, James E. Talmadge, Alison M. Badger

Journal:

International Journal of Immunopharmacology

Year:

1991

Language:

english

File:

PDF, 724 KB

english, 1991

15

Effects of SK&F 105685, a novel anti-arthritic agent, on immune function in the dog

Johanne M. Kaplan, Alison M. Badger, Elizabeth V. Ruggieri, Barbara A. Swift, Peter J. Bugelski

Journal:

International Journal of Immunopharmacology

Year:

1993

Language:

english

File:

PDF, 947 KB

english, 1993

16

Structure-activity studies of rapamycin analogs: evidence that the C-7 methoxy group is part of the effector domain and positioned at the FKBP12-FRAP interface

Juan I. Luengo, Dennis S. Yamashita, Damien Dunnington, Arda Konialian Beck, Leonard W. Rozamus, Hwa-Kwo Yen, Mary J. Bossard, Mark A. Levy, Annalisa Hand, Tonie Newman-Tarr, Alison Badger, Leo Faucet

Journal:

Chemistry & Biology

Year:

1995

Language:

english

File:

PDF, 4.97 MB

english, 1995

17

Selective immunomodulatory activity of SK&F 106615, a macrophage-targeting antiarthritic compound, on antibody and cellular responses in rats and mice

Alison M Badger, Tonie M Newman-Tarr, Jennifer L Satterfield

Journal:

Immunopharmacology

Year:

1997

Language:

english

File:

PDF, 247 KB

english, 1997

18

Atiprimod (SKandF 106615), a novel macrophage targeting agent, enhances alveolar macrophage candidacidal activity and is not immunosuppresive in candida-infected mice

Alison M. Badger, Jeffrey A. Handler, Caroline A. Genell, Danuta Herzyk, Elizabeth Gore, Rodd Polsky, Lee Webb, Peter J. Bugelski

Journal:

International Journal of Immunopharmacology

Year:

1999

Language:

english

File:

PDF, 418 KB

english, 1999

19

Design, synthesis and evaluation of dual domain FKBP ligands

Dennis S. Yamashita, Hye-Ja Oh, Hwa-Kwo Yen, Mary J. Bossard, Martin Brandt, Mark A. Levy, Tonie Newman-Tarr, Alison Badger, Juan I. Luengo, Dennis A. Holt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 351 KB

english, 1994

20

Structure-activity studies of nonmacrocyclic rapamycin derivatives

Dennis A. Holt, Arda L. Konialian, Martin Brandt, Mark A. Levy, Mary J. Bossard, Juan I. Luengo, Tonie Newman-Tarr, Alison Badger

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 307 KB

english, 1993

21

Peptide Aldehyde Inhibitors of Cathepsin K Inhibit Bone Resorption Both In Vitro and In Vivo

Bartholomew J. Votta, Mark A. Levy, Alison Badger, Jeremy Bradbeer, Robert A. Dodds, Ian E. James, Scott Thompson, Mary J. Bossard, Thomas Carr, Janice R. Connor, Thaddeus A. Tomaszek, Lawrence Szewcz

Journal:

Journal of Bone and Mineral Research

Year:

1997

Language:

english

File:

PDF, 666 KB

english, 1997

22

Selective Inhibition of Phospholipases by Atiprimod, a Macrophage Targeting Antiarthritic Compound

Jeffrey A. Handler, Alison Badger, Caroline A. Genell, Anne M. Klinkner, Shouki Kassis, Crystal R. Waites, Peter J. Bugelski

Journal:

Toxicology and Applied Pharmacology

Year:

1999

Language:

english

File:

PDF, 117 KB

english, 1999

23

Induction by immunomodulatory agents of a macrophage antigen recognized by monoclonal antibody 158.2 and correlation with macrophage function

Thomas P. Koestler, Alison M. Badger, David J. Rieman, Russell Greig, George Poste

Journal:

Cellular Immunology

Year:

1985

Language:

english

File:

PDF, 870 KB

english, 1985

24

p38 Mitogen-Activated Protein Kinase Inhibitors— Mechanisms and Therapeutic Potentials

John C. Lee, Shouki Kassis, Sanjay Kumar, Alison Badger, Jerry L. Adams

Journal:

Pharmacology & Therapeutics

Year:

1999

Language:

english

File:

PDF, 267 KB

english, 1999

25

Advances in antiarthritic therapeutics

Alison M. Badger, John C. Lee

Journal:

Drug Discovery Today

Year:

1997

Language:

english

File:

PDF, 1.08 MB

english, 1997

26

EFFECTS OF ANTIGENIC COMPETITION ON IMMUNE RESPONSES TO TUMORS

Arthur H. Glasgow, Alison M. Badger

Journal:

Annals of the New York Academy of Sciences

Year:

1976

Language:

english

File:

PDF, 283 KB

english, 1976

27

Injurious Mechanical Compression of Bovine Articular Cartilage Induces Chondrocyte Apoptosis

Andreas M. Loening, Ian E. James, Marc E. Levenston, Alison M. Badger, Eliot H. Frank, Bodo Kurz, Mark E. Nuttall, Han-Hwa Hung, Simon M. Blake, Alan J. Grodzinsky, Michael W. Lark

Journal:

Archives of Biochemistry and Biophysics

Year:

2000

Language:

english

File:

PDF, 175 KB

english, 2000

28

Prevention of Diabetes and Induction of Non-Specific Suppressor Cell Activity in the BB Rat by an Immunomodulatory Azaspirane, SK&F 106610

Alex Rabinovitch, Wilma L. Suarez, Hui-Yu Qin, Robert F. Power, Alison M. Badger

Journal:

Journal of Autoimmunity

Year:

1993

File:

PDF, 396 KB

1993

29

Culture conditions affecting induction and release of lymphocyte produced proliferation inhibitory factor (PIF)

Alison M. Badger, Sidney R. Cooperband, Jon A. Green

Journal:

Cellular Immunology

Year:

1973

Language:

english

File:

PDF, 1.01 MB

english, 1973

30

Studies on the mechanism of action of proliferation inhibitory factor (PIF)

Alison M. Badger, Sidney R. Cooperband, Jon A. Green

Journal:

Cellular Immunology

Year:

1974

Language:

english

File:

PDF, 864 KB

english, 1974

31

An immunostimulatory substance in the ascites fluid of patients with cancer metastatic to the peritoneum

Alison M. Badger, Sidney R. Cooperband

Journal:

Cellular Immunology

Year:

1979

Language:

english

File:

PDF, 720 KB

english, 1979

32

1-Substituted 4-Aryl-5-pyridinylimidazoles: A New Class of Cytokine Suppressive Drugs with Low 5-Lipoxygenase and Cyclooxygenase Inhibitory Potency #

Boehm, Jeffrey C., Smietana, Juanita M., Sorenson, Margaret E., Garigipati, Ravi S., Gallagher, Timothy F., Sheldrake, Peter L., Bradbeer, Jeremy, Badger, Alison M., Laydon, Jeffrey T., Lee, John C.,

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 252 KB

english, 1996

33

Antiarthritic and supressor cell inducing activity of azaspiranes: structure-function relationships of a novel class of immunomodulatory agents

Badger, Alison M., Schwartz, David A., Picker, Donald H., Dorman, James W., Bradley, Fontaine C., Cheeseman, Elaine N., DiMartino, Michael J., Hanna, Nabil, Mirabelli, Christopher K.

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 1005 KB

english, 1990

34

Induction of non-specific suppressor cells in normal lewis rats by a novel azaspirane SK&F 105685

Badger, Alison M., King, Andrew G., Talmadge, James E., Schwartz, David A., Picker, Donald H., Mirabelli, Christopher K., Hanna, Nabil

Journal:

Journal of Autoimmunity

Year:

1990

Language:

english

File:

PDF, 893 KB

english, 1990

35

Caffeine self-administration and withdrawal: incidence, individual differences and interrelationships

Hughes, John R., Oliveto, Alison H., Bickel, Warren K., Higgins, Stephen T., Badger, Gary J.

Journal:

Drug and Alcohol Dependence

Year:

1993

Language:

english

File:

PDF, 798 KB

english, 1993

36

Cyclosporin Analogs Modified in the 3,7,8-Positions: Substituent Effects on Peptidylprolyl Isomerase Inhibition and Immunosuppressive Activity Are Nonadditive

Hu, Ming-Kuan, Badger, Alison, Rich, Daniel H.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 846 KB

english, 1995

37

Modulation of Rat Bronchoalveolar Lavage Cell Function by the Intratracheal Delivery of Interferon-γ

BADGER, ALISON M., MEUNIER, PAUL C., WEISS, RACHELLE A., BUGELSKI, PETER J.

Journal:

Journal of Interferon Research

Year:

1988

Language:

english

File:

PDF, 1.06 MB

english, 1988

38

In Vitro Models for Investigation of the Effects of Acute Mechanical Injury on Cartilage

Patwari, Parth, Fay, Jakob, Cook, Michael N., Badger, Alison M., Kerin, Alex J., Lark, Michael W., Grodzinsky, Alan J.

Journal:

Clinical Orthopaedics and Related Research®

Year:

2001

Language:

english

File:

PDF, 278 KB

english, 2001

39

INDUCTION OF NONSPECIFIC X-IRRADIATION-RESISTANT SUPPRESSOR CELL ACTIVITY IN VIVO AND PROLONGATION OF VASCULARIZED ALLOGRAFT SURVIVAL BY SK&F 105685, A NOVEL IMMUNOMODULATORY AZASPIRANE

SCHMIDBAUER, GEORG, HANCOCK, WAYNE W., BADGER, ALISON M., KUPIEC-WEGLINSKI, JERZY W.

Journal:

Transplantation Journal

Year:

1993

File:

PDF, 792 KB

1993

40

ABROGATION BY RAPAMYCIN OF ACCELERATED REJECTION IN SENSITIZED RATS BY INHIBITION OF ALLOANTIBODY RESPONSES AND SELECTIVE SUPPRESSION OF INTRAGRAFT MONONUCLEAR AND ENDOTHELIAL CELL ACTIVATION, CYTOKINE PRODUCTION, AND CELL ADHESION1,2

SCHMIDBAUER, GEORG, HANCOCK, WAYNE W., WASOWSKA, BARBARA, BADGER, ALISON M., KUPIEC-WEGLINSKI, JERZY W.

Journal:

Transplantation Journal

Year:

1994

File:

PDF, 1.01 MB

1994

41

The ability of low doses of caffeine to serve as reinforcers in humans: A replication.

Hughes, John R., Oliveto, Alison H., Bickel, Warren K., Higgins, Stephen T., Badger, Gary J.

Journal:

Experimental and Clinical Psychopharmacology

Year:

1995

Language:

english

File:

PDF, 912 KB

english, 1995

42

27-O-Demethylrapamycin, an Immunosuppressant Compound Produced by a New Strain of Streptomyces hygroscopicus.

BOX, STEPHEN J., SHELLEY, PETER R., TYLER, JOHN W., VERRALL, MICHAEL S., WARR, STEPHEN R. C., BADGER, ALISON M., LEVY, MARK A., BANKS, RHONA M.

Journal:

The Journal of Antibiotics

Year:

1995

Language:

english

File:

PDF, 201 KB

english, 1995

43

[Annual Reports in Medicinal Chemistry] Volume 33 || New Treatments for Arthritis

Badger, Alison M.

Year:

1998

Language:

english

File:

PDF, 787 KB

english, 1998

44

[Methods in Cell Biology] Volume 14 || Chapter 28 Selection of Synchronized Populations of HeLa Cells

Badger, Alison M.

Year:

1976

Language:

english

File:

PDF, 466 KB

english, 1976

45

Activation of Rat Alveolar Macrophages by Gamma Interferon to Inhibit Toxoplasma gondii In Vitro

Badger, Alison M., Hutchman, John S., Sung, Cheng-Po, Bugelski, Peter J.

Journal:

Journal of Leukocyte Biology

Year:

1987

Language:

english

File:

PDF, 1.30 MB

english, 1987

46

Enhanced Superoxide Production by Rat Alveolar Macrophages Stimulated In Vitro With Biological Response Modifiers

Badger, Alison M.

Journal:

Journal of Leukocyte Biology

Year:

1986

Language:

english

File:

PDF, 1.12 MB

english, 1986

47

A Longitudinal Study of the Feline Faecal Microbiome Identifies Changes into Early Adulthood Irrespective of Sexual Development

Deusch, Oliver, O’Flynn, Ciaran, Colyer, Alison, Swanson, Kelly S., Allaway, David, Morris, Penelope, Badger, Jonathan H.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.35 MB

english, 2015

48

âMyxoedema madnessâ with Capgras syndrome and catatonic features responsive to combination olanzapine and levothyroxine: TableÂ 1

Shlykov, Maksim A, Rath, Swapnil, Badger, Alison, Winder, Gerald Scott

Journal:

BMJ Case Reports

Year:

2016

File:

PDF, 236 KB

2016